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The roles of mesenchymal stem cells in gastric lesion and regeneration : applica- tions in gastric diseases

Journal Volume 76 - 2013
Issue Fasc.1 - Case series
Author(s) Y. Gong, L. Song, C. Yang, Y. Che, Q. Chen, B. Wu
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(1) Gastrointestinal Department of Southern Building, PLA general hospital, Beijing, P.R.China ; (2) Michael Smith Laboratories, 301-2185 East Mall, University of British Columbia, Vancouver, BC, Canada V6T 1Z4. Gong Y. and Song L. contribute equally to this work.

In recent years, many studies have focused on the roles of mesenchymal stem cells (MSCs) due to their contribution to tissue regeneration and tumorigenesis. However, the full profile of the roles of MSCs in gastric diseases has not been established. In this review, we aim to provide an overview on the roles of MSCs on cell lesion and regeneration in gastric diseases, including gastric ulcer, premalignant conditions and cancer. We will also discuss the mechanisms underlying the behaviors of MSCs in these diseases. (Acta gastroenterol. belg., 2013, 76, 10-14).

© Acta Gastro-Enterologica Belgica.
PMID 23650776